BOULDER, CO – NOVEMBER 03: A general view of the stadium as the Stanford Cardinal face the Colorado Buffaloes at Folsom Field on November 3, 2012 in Boulder, Colorado. The Cardinal defeated the Buffaloes 48-0. (Photo by Doug Pensinger/Getty Images)Week 11 of the college football season kicked off on Thursday night with a major upset. Wake Forest traveled to North Carolina to take on the NC State Wolfpack in an All-ACC affair.The Demon Deacons used a late touchdown to take a 27-23 lead and the intercepted a pass from Wolfpack quarterback Ryan Finley to ice the game. It was just the second loss of the season for No. 14 NC State.That games serves as a nice appetizer for the upcoming Saturday slate of games. Before those games kick off, ESPN’s panel of experts revealed their picks for the weekend’s biggest games.Among the picks were two major upset picks.Edward Aschoff and David Hale both predict Colorado will take down No. 8 Washington State on Saturday afternoon.The Cougars enter this game with just one loss on the season – a field goal loss at USC. Can the Buffaloes end their four-game skid and finally get back in the win column?Washington State and Colorado kick off on Saturday at 3:30 p.m. ET on ESPN.